Isaac Dice Room: The Most OP Item In The Game! — Key Highlights
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Comprehensive Findings & Archive
Depending on the dice roll on the floor there is different effects.
If you're having an amazing run and find a dice room that you don't know the effet of, i'd be careful, it may shuffle you to worse items.
If you want a damage item then mom's knife is the best standalone damage item for pure damage output, though epic fetus is also great and effectively gives you infinite bombs as a bonus.
I found a dice room that changed all my crappy items(really crappy) and got lord of the flies + orbital stationary tears of fear/charm that was also piercing and spectral and gigantic.
Photographic Archive
